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Protein Misfolding: A Common Thread Connecting Many Diseases

Saturday Science Exploration Series

Proteins are the workhorses of our cells, carrying out essentially every role related to catalysis, cell structure and transport.  Proteins are synthesized as linear polymers but must fold into diverse 3D shapes in order to carry out their diverse functions.  Failure of a protein to fold correctly can lead to a wide variety of devastating human diseases, spurring the search for common mechanisms to help keep protein folding on the correct path.

Presenter: Patricia Clark, O’Hara Professor of Chemistry & Biochemistry and Concurrent Professor of Chemical & Biomolecular Engineering

 

Originally published at science.nd.edu.