Histology Core

Instruments and Services


The Notre Dame Histology Core (NDHC) provides a means to examine biological processes  in mice , rats, frogs, zebra fish, fruit flies, sheep bone, and even human tissue by use of immunohistochemical techniques and pathology. The facility is located in Freimann Life Sciences and it is equipped with a Shandon Citadel Tissue Processor, Leica microtome, Tissue-Tek III embedding station, and a new Leica Cryostat with a special Tungsten blade attachment capable of slicing through bone.

Services include tissue fixation, processing, embedding, sectioning, and staining of paraffin or frozen tissue sections. Staining of tissue sections ranges from routine H&E’s (Hematoxylin-Eosin) to special stains demonstrating specific tissue structures. The Core offers immunohistochemical staining with antibodies supplied by investigators.


Researchers can be trained to use our devices, or services can be provided by experienced staff.  Contact the  assistant director of biological imaging, Sarah Chapman, for training, consultation, and/or experimental service.


Rates are updated annually.